Endocrine Abstracts

Long acting somatostatin analogues (SMS) are extensively used as second and even first line treatment of acromegaly. Except of the inhibition of GH secretion, somatostatin is a potent inhibitor of insulin secretion from the pancreatic b- cells. As defects of glucose homeostasis are very common in acromegaly, we decided to examine the effect of the control of GH hypersecretion with SMS on glucose metabolism.We study 44 acromegalic patients divided in 3 gr...

Primary aldosteronism is diagnosed with increasing frequency, especially between patients with hypertension. Thus, a reliable screening test is necessary to avoid costly and demanding diagnostic procedures to this population. The aim of the present study is the evaluation of aldosterone to renine ratio (A/R) in the diagnostic algorithm of patients with hypertension with or without adrenal insidentaloma.A total of 115 subjects were studied: 13 patients wi...